For a 5000 rpm motor, I would recommend a 9.00:1 to 9.25:1 static compression ratio, matched with a cam that has 208 to 213 degrees intake duration at 0.050" tappet lift and operates from 1,000-5,000 rpm's. Here's an example of what I might use.....
http://www.summitracing.com/parts/hr...5-10/overview/
Howards, Hyd. Roller Cam & Lifter Kit, Chev SB, Retro-Fit - Competition Products
More cam than this will require more static compression ratio and will raise the operating rpm range beyond the ability of your heads to fill the cylinders.

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